Many people being already mindful of what they eat, exercising regularly but are still seeing no improvements in their biomarkers such as blood pressure, blood sugar or cholesterol. A new report suggests that inflammation induced by nutrients deficiencies maybe in cause.
43 healthy lean and overweight/ obese adults, who served as their own controls consumed twice daily nutrient-dense bar (fibre, iron, B vitamins, magnesium, zinc,) intended to fill gaps in western diets without other dietary/ lifestyle requirements.
It appeared that People who were overweight/obese moved in a healthier metabolic direction (e.g., improved HDL, LDL, insulin, glucose, etc.), and some lost weight by just eating small, low-calorie, nutrient bars each day for two months, without any additional requirements.
However, the improvements were mostly seen in people with lower levels of inflammation; high chronic inflammation prevented people from experiencing these improvements. 
Take home message
This study highlights two important findings:
Lowering inflammation in the body may help weight loss efforts and get you healthier. Try eating more anti-inflammatory food such as turmeric, ginger, polyphenol rich berries, nuts ,cruciferous vegetables,..
For people with lower inflammation levels, filling gaps in the diet with nutrients, vitamins, and minerals vital may help your biomarkers improved (cholesterol, blood sugar,.. ) meaning you need a nutrient rich diet.
McCann,J.C., Shigenaga, M.K., Mietus-Snyder,M.L., Lal, A., Suh,J.H., Krauss,R.M., Gildengorin,G.L., & al.,A multicomponent nutrient bar promotes weight loss and improves dyslipidemia and insulin resistance in the overweight/obese: chronic inflammation blunts these improvements. The FASEB Journal, 2015; 29 (8): 3287